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Dr Shock MD PhD
Pregnancy requires many adaptations to new situations. These changes are accompanied by massive neuroendocrine changes leading to adaptations organized by the mother’s brain. These changes are necessary for the different phases of pregnancy and motherhood.
First optimization is needed for the growth and protection of the fetus, next parturition has to be timely and uncomplicated, next maternal behavior such as caring and defending the young is important together with the start of lactation. It’s not easy to understand the complex interaction between female- and pregnancy hormones and their interaction with the maternal brain.
At the start of pregnancy the brain controls the increased appetite necessary for the pregnancy and the expansion of the blood volume as well as deeper breathing. The brain also prevents further ovulations through the pituitary gland.
The most important female hormones secreted in massive amounts during pregnancy are oestrogen en progesterone. They are very lipid soluble and easily penetrate the brain. Their ratio change the balance …
