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Dr Shock MD PhD
When feeling down good music can cheer you up. But when depressed, I mean clinically depressed, can you enjoy music? How is music enjoyment processed by the brain and how is this influenced by depression?
All participants of this study enjoyed their favorite music more than the neutral music and depressed patients didn’t differ from the healthy subjects in scores for enjoyment of favorite music nor on the difference between the favorite and neutral music. On the fMRI the depressed patients showed less activation of parts of the brain: the medial orbital frontal cortex, the nucleus accumbens and the ventral striatum. In the pictures above you can see the areas more active in healthy controls compared to depressed patients.
These brain regions are known to be involved …

